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Beilstein J. Org. Chem. 2018, 14, 2510–2519, doi:10.3762/bjoc.14.227
Graphical Abstract
Figure 1: N-Aryl-3,4-dihydroquinazolines 1.
Scheme 1: Synthetic pathway leading to N-aryl-3,4-dihydroquinazolines 1.
Scheme 2: Synthesis of compounds 2.
Figure 2: Reaction intermediate in the synthesis of compound 2a.
Scheme 3: Addition–elimination mechanism for the heterocyclization.
Scheme 4: Proposed mechanism involving an intermediate nitrilium ion.
Beilstein J. Org. Chem. 2017, 13, 1470–1477, doi:10.3762/bjoc.13.145
Figure 1: 3,4-Dihydroquinazolines 1 and 1,4-dihydroquinazolines 2.
Scheme 1: Synthetic pathways for the preparation of 3,4-dihydroquinazolines 1 and 1,4-dihydroquinazolines 2.
Scheme 2: Synthesis of compounds 3a–c.
Scheme 3: Benzylic oxidation of 1,4-dihydroquinazolines (a) and 3,4-dihydroquinazolines (b).
Beilstein J. Org. Chem. 2016, 12, 2026–2031, doi:10.3762/bjoc.12.190
Scheme 1: Our previous and present work.